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This modification, performed by the acetyltransferase (KAT) enzyme p300/KAT3B, which is absent in yeast, distinctly marks promoter-proximally paused polymerases.
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All cells that result from proliferation and differentiation of a distinctly marked HSPC will carry identical markings defined by the location of the original viral vector integration site (VIS).
They formed up and soon their position was "distinctly marked by the cartridge papers dropped at this time".
But as the only entrance of its kind on any of the surrounding streets, it is distinctly marked as a thing apart, as clearly "other" as servants' quarters.
Many of the MacLehose's 10 distinctly marked sections of one- to two-hour hikes are accessible by taxi and bus.
It is rare for the English-language dominance of the musical-comedy genre to be breached by other countries, as France did with Irma la Douce (1956) or pre-Nazi Germany did with Die Dreigroschenoper (Threepenny Opera, 1928) and Im weissen Rossl (1930; White Horse Inn); but in most European countries except Britain the line between musical and operetta (see below) is less distinctly marked.
Dickens said Nickleby was about how childhood impressions are more real than any we receive in adult life: "Perhaps a word, a laugh, some slight distress, a passing thought or fear - and yet more strongly and distinctly marked, and better far remembered, than the hardest trials or severest sorrows of but a year ago".
The mazes are networks of distinctly marked rooms randomly interconnected by doors that open probabilistically.
The palynological data confirm the geologic structure of the section: The recognized spore-pollen spectra distinctly mark the first half of the Holocene and reflect the landscape changes.
Moreover, the impact of the geomagnetic storms are distinctly marked in the daily time series of amplitudes of DW1, SW2 and SPW1.
Moreover, the distinctly marked lower cytotoxicity of compounds 7 and 12 against the normal cell line – human skin fibroblasts (HSF) and almost several-fold higher against the examined cancer cell lines was ascertained.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com