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Differences in survival between distinctive survival groups were analyzed with the log-rank test.
Differentially expressed genes between two distinctive survival groups were directly identified by two-class analysis (students' t test) of microarray gene expression data using the SAM software.
Significantly enriched gene sets were then identified by performing gene set enrichment analysis (measuring the degree of differential gene expression in a gene set) between two distinctive survival groups based on microarray expression data using SAM-GS software [8].
Basal-like breast cancers have distinctive survival patterns, many relapses and deaths during the first 5 years after diagnosis, but fewer events after this period [ 32], indicating that basal-like breast cancers encompass both poor and good prognostic subgroups responding variably to conventional therapies.
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Metabolic changes affecting mitochondria function inside cancer cells endow these cells with distinctive properties and survival advantage worthy of drug targeting, mitochondria-targeting drugs offer substantial promise as clinical treatment with minimal side effects.
Cells which survive chemotherapy may have a distinctive biology (e.g. active survival pathways, quiescent cell cycle status) compared to the bulk of cells in the clone, and/or may be protected by the bone marrow niche microenvironment in which they reside.
A lone investor has swooped in and taken control of a struggling political magazine and left investors like Warren E. Buffett with nothing to show for years of patient support -- except the survival of a distinctive neoliberal point of view in the national political debate, which is all they hoped for in the first place.
Much more research is needed to discover the number, extent and survival of these distinctive expressions of pre-modern attitudes, institutions and behaviours, and their contribution to the present landscape.
These data suggests that the RhoA-ROCK and PTEN-AKT signaling pathways mediate distinctive signaling regulating stem cell survival and proliferation although there is a crosstalk between them.
Analysis of the ability of genetic inhibitors to mediate a survival advantage provides distinctive information not provided by standard inhibition assays and may offer information relevant to the in vivo efficacy of these genetic inhibitors.
Survival means developing a distinctive product.Economists who have studied religion agree.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com