The difference in the amount of differentially expressed genes, distinctive gene expression patterns, specific regulated gene lists, pathways and unique gene networks, suggest a specific molecular mechanism for each compound.
Looking for distinctive gene expression patterns in different brain cell types offers a more efficient way to search for genetic alterations implicated in autism and reveals a molecular signature of the disorder.
Defining the source of the distinctive gene expression patterns was facilitated by projecting the expression data for clonal pancreatic cancer cell lines, primary pancreatic duct cultures, and isolated pancreatic islets alongside the data derived from the previous clustering analysis (Figure 1B).
Due to significant differences in their composition, we expected that they will elicit markedly distinctive gene expression patterns.
The results suggest that maturation and aging of the bone marrow define distinctive gene expression patterns that effect both tissue-specific and housekeeping genes.
In this study we found that low dose-rate exposure can result in distinctive gene expression patterns compared with acute exposures.
We characterised two distinctive gene expression patterns to aid in the stratification of primary colorectal neoplasms among Malaysian patients with CRC.
Our analysis revealed that the different compartments of the female mosquito midgut display distinctive gene expression patterns that correlate with their specific functions.
Having defined distinctive gene expression patterns among the PCT subtypes as well as between PCTs and BCLs, we next sought to examine how well our mouse models recapitulate human phenotypes as measured by relative similarities of gene expression patterns.
Although there were many similarities in immune function and stress response genes, we found that low dose-rate exposure can result in distinctive gene expression patterns compared with acute exposures.
