Sentence examples for distinctive foci from inspiring English sources

Expanded CUG repeats sequester nuclear proteins and accumulate into distinctive foci within muscle and neuronal nuclei [ 90].

The only detectable difference between the two wild type CDK inhibitors was the induction of SAHF; only p16INK4a accumulation led to the appearance of these distinctive foci, which were enriched for H3K9Me.

WT virus expressed DNA binding protein (DBP) from the E2A gene in distinctive foci within the cell nuclei that are indicative of active replication [ 42]; it also expressed a high level of late proteins as expected of a normally progressing infection 20 hours post-infection (h.p.i.; Figure 6B panels a-c).

Moreover, it should be kept in mind that, contrarily to what happens in lesions where the targets of a radiopharmaceutical are membrane bound receptors, TNF α is also a soluble molecule and a possible washout or low concentration in the lesions could prevent the visualization of distinctive foci.

Grim has maintained a distinctive focus, Mr. Celkupa said — even after becoming a working agent himself last fall, making clients of several people who had come to know him through the blog.

5. See Conee and Feldman 1985 & 2004 for a general presentation of their 'evidentialist' view; see Connee & Feldman 2001 for a distinctive focus on their internalism.

The distinctive focus of ancient skepticism on belief becomes clearer once we consider a third concept that figures centrally in ancient discussions: criterion of truth.

Like existentialism and French personalism, phenomenological realism was a response to German idealism, though it bore a distinctive focus on epistemological questions.

Though projects can be key tools for introducing novel work practices, 35 they offer benefits, including a distinctive focus, identity and drive, excitement and interest.

Some senescent cells form distinctive heterochromatic foci (SAHFs) [9], [10], and many harbor markers of persistent DNA damage [2], [11], [12], [13], [14].

Distinctive HIRA foci were able to be detected inside PML bodies as early as one day after 4OHT-treatment, at which point the ASF1a colocalization was weak or non-existent (Figure 2A), in contrast to the strong ASF1a foci at day 4 (Figure 1C).