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Bioinformatic analysis of the various dockerin modules showed distinctive conservation patterns within their two Ca2+-binding repeats and their flanking regions.
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Enhancer elements are often predicted from their distinctive sequence conservation.
MedPIWI shows distinctive residue conservation patterns that indicate an involvement in ds nucleic acid binding but no catalytic activity.
We analyzed two benchmark datasets and found that linear B-cell epitopes possess distinctive residue conservation and position-specific residue propensities which could be exploited for epitope discrimination in silico.
Strongly conserved intron patterns, as well as distinctive patterns of sequence conservation, distinguish the six types of NTMC2 genes.
The JTB structure has a distant relationship to the midkine/pleiotrophin fold, particularly in the conservation of distinctive disulfide bridge patterns.
I have classified the collection into homologous gene families according to distinctive patterns of sequence conservation and intron position.
Kolbe et al. (2004) introduced a measure they called 'Regulatory Potential' which combines phylogenetic conservation with distinctive hexamer frequency profiles to identify possible regulatory regions.
Of the aforementioned 6,532 positive predictions, 815 showed distinctive features of evolutionary conservation as analyzed by orthologous group enrichment (False discovery rate (FDR) < 0.05).
We have compiled a dataset of 580 experimentally verified granzyme B cleavage sites and found distinctive patterns of residue conservation and position-specific residue propensities which could be useful for in silico prediction using machine learning algorithms.
In this paper, we have compiled a dataset of 580 experimentally verified granzyme B cleavage sites and found distinctive patterns of residue conservation and position-specific residue propensities which could be useful for in silico prediction using machine learning algorithms.
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