This distinctive clone was presumed to evolve carrying multiple β-lactamase genes during the process of adaptation to the hospital environments of high antibiotics pressure, making it possible to successfully disseminate in the ICUs.
While the distinct clone sizes varied by three orders of magnitude, we found that collectively, they form a steady-state clone size-distribution with a distinctive shape.
Among SA isolates, clones with distinctive genetic backgrounds are responsible for the majority of infections within a host type, although the distinct bovine clone groups are often interspersed among the human clone groups in a manner suggesting that human-associated SA clones were the evolutionary precursors to modern bovine specialist SA clones [11], [13], [15], [16].
We propose that selection from responding clones with distinctive TCRs on the basis of functional avidity can direct a preference away from Th1 effector responses, favoring Th2 cytokines.
Recent genetic studies on acute lymphoblastic leukaemia at the single cell level reveal a complex non-linear, branching clonal architecture with sub-clones having distinctive genetic signatures.
Among the distinctive characteristics of the international clones, multidrug resistance to antimicrobial agents is clearly the most salient, as noted early [7], [9], [10].
All of the sequences from the other primates have distinctive haplotype sequences confirmed by clone sequencing.
Another distinctive gene expression signature in transformed clones was Ly6A and Ly6E.
We could isolate more than one cDNA clone from a single distinctive differential display band.
Small clusters of sequence variants that coincide with the memory B-cell subset can be seen, further suggesting that selection for the clone members could be distinctive within the PB and memory B-cell subsets.
In both, the restaurants are not franchised clones of each other, but establishments with distinctive personalities of their own.
