NMJs in all three muscle types from Rab18 −/− mice showed distinctive large accumulations at both stages, progressing from 30% of terminals in early symptomatic muscles to 60% by mid-late-symptomatic timepoints in FDB and lumbrical muscles (Fig. 4J K).
Once inside the cancer cell, the nanosized therapeutic agent's distinctive capabilities allow accumulation and retention of these agents within the tumor for an extensive amount of time.
From its initial description (Alexander, 1949), the disease was associated with distinctive pathology involving accumulations of cytoplasmic protein aggregates within the cell bodies and processes of astrocytes, known as Rosenthal fibres, which contain GFAP and other proteins.
When activated by an agonist ligand in preadipocytes, a differentiation program is stimulated; in turn, morphological changes, lipid accumulation, and distinctive adipocyte gene expression take place [ 14– 17].
Comparative analysis of repetitive sequences between the sex determining region of papaya X chromosome and orthologous autosomal sequences of Vasconcellea monoica, a close relative of papaya lacking sex chromosomes, revealed distinctive differences in the accumulation of Ty3-Gypsy, suggesting that the evolution of the papaya sex determining region may accompany Ty3-Gypsy element accumulation.
The IC perspective has emerged alongside RBT as a complementary viewpoint but has a distinctive practitioner bent emphasizing resource accumulation and deployment in the value creation process.
In the assay, senescence-associated β-galactosidase catalyzes the hydrolysis of X-gal, which results in the accumulation of a distinctive blue color in senescent cells.
Smith also saw that the competitive search for capital accumulation would impart a distinctive tendency to a society that harnessed its motive force.
A distinctive temperature history due to heat accumulation was identified as an important feature for FSW of small-dimension pipes, leading to distinctive variations of surface condition, macro-/micro-structure along the circumferential weld seam.
HFD induced obesity is characterized by dyslipidemia, hyperglycemia and insulin resistance, increased fat accumulation, impaired glucose metabolism, distinctive visceral adiposity, hyperinsulinemia and hepatic steatosis in rodents [ 35, 36].
