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The method attempts to optimise between-cluster variation whilst minimising variation within clusters, thus producing a clearer distinction of clusters [ 80].
The discriminative characters analysis of DGGE profiles indicate that the bands of box B and box C, which are different in clusters 1 4 versus cluster 5 6, might generate the distinction of clusters.
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Although the four clusters were defined by two basic responses, normalisation of the data across all of the tissues in TobEA allowed further distinction of the clusters.
Then, the distinction of such clusters with respect to HRI-diff from that of renal parenchyma shows the quantified characteristic of HRI.
The NA-NOSE signals were analysed with standard principal component analysis (PCA) (Roeck et al, 2008), which shows the variability of the experimental data and allows the distinction of tentative clusters through visual perception of the 2D principal component (PC) plots.
However, group 3 displayed the largest differentiations (0.28 < F ST < 0.45; P < 0.001) in agreement with the early distinction of this cluster in the first (K = 2) analysis of STRUCTURE.
An example of hierarchical layout is shown in Figure 1c and Figure 2 (below) In Arena3D, we make a distinction between layout and clustering algorithms – clustering algorithms are layout methods that organize data into a distinct number of clusters.
This analysis confirms the distinction of the minimotif clusters derived by the sequence based-analysis.
The correct taxonomic distinction of the phylogenetic clusters of this genus is of great importance for their industrial applications and investigations of their medical relevance.
This result is consistent with recent findings [25], [35] and fully supports the taxonomic distinction of these two sequence clusters [44].
The clustering quality is measured in terms of the density of the clusters, as well as the distinction between clusters and the closeness of the clusters to some reference clusters.
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