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Figure 2B illustrates how distinct the two clusters were from one another, indicating that these two clusters are naturally occurring within the top discriminating gene set.
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The nuclear genomes of the two clusters remained distinct in sympatry, particularly at three syntopic sites, suggesting the existence of reproductive isolation between the identified clusters.
The two clusters have distinct transcriptional profiles, indicating that intercellular differences in gene expression cannot be attributed solely to random stochastic fluctuations.
In addition, individual assignment probabilities declined as K increased to 3 and 4. When K = 2, the two clusters were distinct with 95% (230/243) of the individuals assigned with > 90% probability to one of the clusters.
We considered three scenarios for datasets with two clusters: the two clusters have some common conditions but distinct genes); the two clusters have some common genes but distinct conditions); and two clusters have both common genes and conditions), in which case an additive model is assumed for the overlapping part.
This optimal number was also confirmed by clinical interpretation of the patterns of development of DR, which were distinct in the five cluster model.
The distinct appearance of the three clusters in phasor diagrams of trophozoite- IRBCs (see Fig. 8C) suggests the formation of microdomains within the host cell cytoplasmic environment, in which hemoglobin appears largely excluded from close contact with calcein.
The cerebellar control samples display a GPCR expression profile that is very distinct from each of the five clusters of medulloblastoma tumors (clusters "A," "B," "C," "D" and "E;" Figure 1).
We interpreted the three clusters as distinct phases in the BAT to WAT transition.
Transcripts of distinct families showed heterogeneous distribution in the five clusters.
The three clusters showed distinct survival rates, with patients whose tumors fell into cluster 3 having extremely poor survival (log-rank test p = 3e-11, Fig. 4e).
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