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We therefore assume that KRAB zinc finger genes/proteins play especially important roles in differentiation processes in fetal brain and testis, e.g. by switching off distinctive target genes in distinct temporal and spatial patterns.
Immune, fibrotic, vascular and myogenic cells appear with distinct temporal and spatial kinetics after muscle injury.
We show that K6+ and K8+/K14+ putative mammary progenitor cells arise during embryogenesis with distinct temporal and spatial distributions.
These results indicate a distinct temporal and spatial relationship between the clinical course of disease and the cellular localization of HMGB1.
Expression profiling indicated that most of the LSGs expressed in various tissues of sweet orange and some of them exhibited distinct temporal and spatial expression patterns.
We report that limb hairy2 expression is an output of simultaneous FGF and SHH activities, with distinct temporal and spatial signaling properties.
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Imaging approaches offer the distinct advantages of providing high temporal and spatial resolution, as well as the high sensitivity necessary to detect early indicators of oxidative stress in cells exposed to environmental agents.
Indeed, distinct integrins alpha chains showed both temporal and spatial pattern expression differences in FC during mid- and late oogenesis [46] and newly synthesized basolaterally localized integrins are involved in the transition from columnar to cuboidal morphology in the follicular epithelium [34].
Delimiting distinct chromatin domains is essential for temporal and spatial regulation of gene expression.
Vascular response to CSD propagates with temporal and spatial characteristics, which are distinct from those of the underlying parenchyma, suggesting a distinct mechanism for vascular conduction.
In addition, our results suggest a modular architecture of the regulatory machinery, in which the temporal and spatial regulations are distinct.
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