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Because Cdc15's and Imp2's SH3 domains are functionally interchangeable, collaborating to recruit proteins required to stabilize the CR (Ren et al., 2015; Roberts-Galbraith et al., 2009), we tested whether the unique function of Imp2 is dictated, at least in part, by distinct structural and functional properties of its F-BAR domain.
An organ is a group of tissues that constitutes a distinct structural and functional unit.
The human cerebral cortex possesses distinct structural and functional features that are not found in the lower species traditionally used to model brain development and disease.
Lymph nodes are key centers of immune reactivity, organized into distinct structural and functional modules including the T-cell zone, fibroblastic reticular cell (FRC) network and the conduit system.
Asthma is an inflammatory disorder of the conducting airways which undergo distinct structural and functional changes leading to non-specific bronchial hyperresponsiveness (BHR) and airflow obstruction that fluctuate over time.
Neuron cells are highly polarized and consist of three distinct structural and functional domains with unique morphologies: one with large and compact cell body that is called soma; one with thin and long axon; and one with numerous thick dendrites with branches.
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Compartmentalization of chromatin into distinct structural and likely functional domains may not be required at the late one-cell stage since the genome is uniformly under-expressed, the transcript and protein requirements are supplied maternally.
There are six known members of the IGFBP family, which share distinct structural characteristics and functional activities.
The mammalian brain is divided into distinct regions with structural and functional similarities and differences.
Detailed inspection showed that these detached high peaks are mostly due to the different 200-amino acid segments (e.g. anterior and posterior portions) derived from one protein, which have distinct oligonucleotide compositions and likely represented distinct structural and/or functional domains of the respective protein.
Here we have performed further phylogenetic analysis of rice and Arabidopsis CaCAs, along with protein structure modelling to demonstrate that CaCA members form clearly distinct families with different structural and functional characteristics, and are not all NCXs.
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