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Carnivorous species exercise distinct selectivity.
Interestingly, the chromatographic data demonstrated distinct selectivity trends between the four Fab variant libraries.
The new ligands activate nuclear retinoic acid receptors (RAR, RXR) with distinct selectivity patterns, as determined in genetically engineered 'reporter' cells.
KNI-1931 showed distinct selectivity against HIV proteases and high potency against drug-resistant strains, surpassing those of Ritonavir and Nelfinavir.
However, in the presence of RGS14, complex formation showed distinct selectivity towards B-Raf and Raf-1, but not A-Raf, in terms of the amount of H-Ras(G12V) co-precipitated.
However, each TKI is associated with a distinct selectivity profile 9– 11.
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In fact, several distinct binding sites have been proposed within the transmembrane helices, which may communicate allosterically despite their distinct selectivities.
Enzymes with high catalytic activity and distinct substrate selectivity have also been utilized as clinical diagnostic tools for identifying target analytes.
Results indicate that the metallic formates exhibit different CH4 adsorption capacities and distinct CH4/N2 selectivity in a sequence of Ni > Co > Mg > Mn analogue owing to their varied CH4 affinities.
The results show that both sanguinarine and nitidine bind preferentially to DNA containing alternating GC base pairs [d TGCGCA 2], while chelerythrine exhibits quite distinct sequence selectivity from sanguinarine, which shows a high specificity for DNA containing contiguous GC base pairs [5′-TGGGGA-3′/3′-ACCCCT-5′ [5′-TGGGGA-3′/3′-ACCCCT-5′ [5′-TGGGGA-3′/3′-ACCCCT-5′ [5′-TGGGGA-3′/3′-ACCCCT-5′ [5′-TGGGGA-3′/3′-ACCCCT-5′
More studies are in progress to understand this distinct binding selectivity.
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