These 1000 sets of ten replicates were analyzed identically to the actual data, and the number of distinct replicates or genomic locations in like replicates across all age categories that met or exceeded the observed LOD score for a given peak was recorded.
Serious research began in the 50s and started along three distinct lines: replicating the eye (difficult); replicating the visual cortex (very difficult); and replicating the rest of the brain (arguably the most difficult problem ever attempted).
The two Igf2-H19 loci are localized in different subnuclear compartments, having distinct replication timing characteristics, and therefore replicated asynchronously in S-phase.
We broke full sibships into distinct trios by replicating parental information.
We systematically discuss what has been learnt regarding these five points since 1999, with emphasis on replicating distinct risk factors and subtypes of human osteoarthritis, and on comprehensive evaluation of the disease in animals, including pathology of all joint tissues, biomarker analysis, and assessment of pain and joint function.
(C and D ) BrdU was detected in the epidermis of His C mutant embryos indicating DNA replication but the pattern of replicating cells was distinct from wild type.
Pasca's method enables him to culture cells in order to form brain organoids with robust structures that are not compromised by cells from other parts of the body, thereby allowing him to more accurately replicate distinct brain regions.
For this purpose we used two mouse models of intestinal inflammation - where disease is driven primarily by innate cells or by CD4+ T cells and thus replicate distinct components of human IBD.
By analyzing three distinct and technically replicated datasets with either ratio- or intensity-based models, we determined that, when applied to the same dataset, intensity-based analysis of dual-color gene expression experiments yields 1) more reproducible results, and 2) is more sensitive in the detection of differentially expressed genes.
This ensures that each disc carries genetically distinct coral organisms, more closely replicating the results of natural reproduction.
