Sentence examples for distinct mutation from inspiring English sources

They focused on 13 mtDNA proteins critical to heat and energy generation and discovered distinct mutation patterns for each group.

Although there is progress regarding our knowledge on the cellular function of desmin within the cytoskeleton, the impact of each distinct mutation is currently not understood at all.

To test the efficacy of FAK inhibition in KRAS mutant NSCLC with distinct mutation cohorts (A: TP53, CDKN2A wild type, B: TP53 wild type, CDKN2A altered, C: TP53 mutant, CDKN2A wild type, and D: TP53 mutant, CDKN2A altered), a phase II multi-center study is currently underway in patients with KRAS mutant NSCLC who have already received one platinum doublet regimen.

Two distinct mutation events were first reported in C. pipiens and C. quinquefasciatus species [5].

To elucidate the frequency of doublets and the distinct mutation pattern and spectrum in the EGFR gene, the epidemiology of doublet mutations in lung cancer is analyzed and compared to that of doublets in the TP53 gene.

Although caused by a distinct mutation, and having a milder phenotype than human GD, MLS nevertheless offers a new animal model for study of GD, and for prospective insights on mechanisms and pathways of skin fibrosis and joint contractures.

EGFR-mutated NSCLC is a genetically heterogeneous disease that includes more than 200 distinct mutations.

The bewildering complexity witnessed by multiple distinct mutations occurring in separate or identical metastases begins to illuminate the vast somatic mutational reservoir present in these tumours.

In total, we found 87 distinct mutations in 14 different genes.

Results: We identified eight distinct mutations in 12 patients from nine families.

This review describes the molecular and cellular characteristics of the eight distinct mutations found so far in humans.