Exact(2)
Blue native gel studies show that Fis1 and Mff reside in complexes of different sizes, suggesting distinct machineries for mitochondrial fission.
snRNAs and replication-dependent histone mRNAs display clear coupling of processing and termination, but these RNAs are processed by distinct machineries.
Similar(58)
These snRNAs are also modified co-transcriptionally with a 5' m7G cap, but 3' end processing is carried out by distinct machinery that generates mature non-polyadenylated termini.
This finding suggests that piRNAs employ a distinct machinery from miRNAs in gene silencing.
The situation is complicated by the fact that retrieval mediated by arginine or lysine-motifs involves distinct machinery.
Although the two pathways utilize fundamentally distinct machinery, apoptosis and autophagy are highly interconnected and share many key regulators.
Large lipid-organized areas of the membrane (lipid rafts) will certainly require a distinct machinery for deformation, budding and scission compared with lipid-disordered areas.
This review will summarize the structural and functional information reported over the past few years on the large machinery required for the 3′-end processing of most pre-mRNAs, as well as the distinct machinery for the 3′-end processing of replication-dependent histone pre-mRNAs, which have provided great insights into the proteins and their subcomplexes in these machineries.
Therefore, like our morphological analyses, also the genetic interaction studies fail to provide any indications that the two nucleators act through distinct molecular machineries of filopodia formation.
Although Nedd8 is arguably the closest relative to ubiquitin, there are sequence differences that require distinct conjugating machineries and deconjugating proteases [27], [49].
Whereas this fundamental principle is conserved from bacteria to mammals, prokaryotes and eukaryotes employ distinct proteolytic machineries for degradation of N-end rule substrates and the stabilizing and destabilizing residues are also different.
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