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While developing an embedded system, an engineer wears three distinct hats.
Many times things relate, but sometimes I have to wear distinct hats.
First, in vitro acetylation assays were carried out to investigate the substrate specificity of distinct HATs.
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In vivo, HAT enzymes are the catalytic subunits of multisubunit protein complexes, and distinct HAT proteins acetylate specific lysine residues within specific N-terminal histone tails.
In addition to GCN5, filamentous fungi possess multiple representatives of distinct HAT families (Borkovich et al., 2004).
This would imply that in a given cell, one HAT is recruited to a particular locus, while in another cell, a distinct HAT is recruited instead to the same locus.
He had quite a distinct look – that hat, very famously his hat that he always wore was placed onto his coffin at his funeral.
The sensitive, bitingly comedic artist Heather Olson has spent years dancing for the great contemporary choreographer Tere O'Connor: his mark is on her work, but the resonant trio "in the river" is a distinct world (again, hats off to Mr. Levasseur's painterly lighting).
Together, these results suggest that each HAT has key roles at different stages of development that seem to be independent of and distinct from other HATs.
Similarly, YGR071C and its homologs in Saccharomycetaceae might derive from an ancestral hAT element, but distinct from the RSF1 hAT ancestor.
Histone acetyl transferases (HATs) play distinct roles in many cellular processes and are frequently misregulated in cancers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com