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We then adopt a multiple-case study approach in order to validate the derivation of the new principles in the context of two, distinct engineer-to-order environments.
Similar observations were made in GEMM of PDA driven by distinct engineered genetic changes as the models tested before: the most striking observation was the increase collagen and CAF in the gemcitabine only treated group.
Two previous studies [22], [23] investigated the effects of ovary-specific conditional inactivation of Brca1 using distinct genetically engineered strains of mice harboring LoxP-flanked alleles of Brca1 [24], [24].
Distinct genetically engineered mice enabled her group to trace and map the origin of these cells.
With Apollo now a distant memory and Mir a distinct liability, the engineer might feel that the grand adventure has not quite fulfilled itself.
Furthermore, we show that Cdk4 utilizes two distinct mechanisms to engineer β-cell mass re-constitution in response to pancreatectomy.
We therefore developed a new localized transfection method to engineer distinct sender and receiver regions.
Ms Kendrick said the food and drink industry was facing an ageing workforce and "a distinct lack of engineers".
Finally, we discuss TALE-based nucleases and genome regulators as distinct categories of engineered site-specific proteins that share a common DBD but differ in their effector domains, hence in their mode of action.
TALENs consist of two distinct domains, an engineered DNA-binding domain derived from the transcription activator-like effector (TALE) that provides the capability and specificity for binding target DNA sequence [ 16, 17], and a non-specific restriction endonuclease Fok I domain fused to the C-terminal of TALE that confers the nuclease activity of TALENs [ 18].
One approach to this goal is to engineer many distinct assembly forms of a single carrier protein or scaffold, to which other proteins of interest can then be readily attached.
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