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Primary ciliary dyskinesia (PCD) is a genetically heterogeneous recessive disorder caused by several distinct defects in genes responsible for cilia beating leading to defective mucociliary clearance often associated with randomization of left/right body asymmetry.
Two distinct defects were identified in the gelsolin-null mammary gland.
Sixteen distinct defects and two possible orientations for the armchair tube (4, 4) are identified.
The results of electrochemical impedance spectroscopy (EIS), X-ray computed tomography (X-CT) confirm non-destructively that the formation of loose and porous defects at the bottom steel-mortar interface results in low corrosion resistance of adjacent steel, whereas few distinct defects can be found at the top steel-mortar interface.
Mutation of PMT1 and PMT4 resulted in distinct defects in cell morphology and cell integrity.
In zebrafish, whereas a hypomorphic mutation in spt5 (the fogm806 allele) displays distinct defects in neuronal development [31], severe truncation (the fogsk8 allele) or deletion (the fogs30 allele) of the gene product causes broad deficits in embryonic development [32].
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In this case stacking fault tetrahedra have been selected as a representative structural, rather than chemically distinct, defect.
This evolution is in contrast to that of our PL spectra which, moreover, do not contain any distinct PL peaks attributable to distinct defect state levels.
Distinct defect-related features that have been discussed in past computational studies are the mechanical load transfer and oscillation damping in MWCNT-based NEMS [19 24].
Plausibly, NBD2-located N1303K creates a distinct defect which unlikely would be corrected by the lumacaftor.
Characterization of sgk3−/− mice demonstrated a distinct defect in hair follicle morphogenesis, producing a wavy hair phenotype.
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