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Thus, the distance between Trp183 and the SE-binding site, the dissimilarity in the biologic effect of the two pathways and their distinct compartmentalization, all suggest that the SE and GABARAP binding sites are neither structurally nor biologically related.
The current study investigated distinct compartmentalization of SP-A and SP-D in the vasculature and lungs.
Shortly after infection, IFN I promoted intracellular Mtb replication, diminished AM numbers, and caused a distinct compartmentalization of Mtb within myeloid cells.
Owing to distinct compartmentalization into an outer and inner membrane, mitochondria have evolved an efficient system for recognition and transport of precursor proteins across membranes.
We conclude that IFNAR1 impacts on Mtb replication in myeloid cells, induces distinct compartmentalization of Mtb among phagocytes in the early phase of infection, and fosters accumulation of PMNs with immunopathologic functions.
This retrospective study aimed to investigate distinct compartmentalization of SP-A and SP-D in the vasculature and lungs by bronchoalveolar lavage fluid (BALF /serum analysis, hydrophilicity and immunohistochemistry.
Similar(53)
The link between ID and CB regions, and simple repetitive regions has been demonstrated, with CB regions of a certain degree of disorder having distinct compartmentalizations and functional category tendencies (13 15).
This distinct nuclear compartmentalization within the cell is recapitulated by both fluorescently tagged proteins (Figure 2A) and FLAG-tagged constructs (Figure S3).
It is nevertheless unlikely that LiTXN1 interacts physiologically with such proteins owing to their distinct subcellular compartmentalization. Using parasites lacking LiTXN2 expression and a digitonin/proteinase K assay, LiTXN1 was confirmed to be absent from the mitochondrion.
Distinct intracellular compartmentalization of IRS-1 and IRS-2 or differential sensitivities of IRS-1 and IRS-2 to negative feedback regulation would also impact the signaling outcomes of these adaptor proteins [ 49, 92].
Using precise sequential transections through the pons to medulla, it was observed that there was compartmentalization of distinct rhythmogenic mechanisms in the ponto-medullary respiratory network, which has rostro-caudal organization.
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