Sentence examples for distinct cellular contexts from inspiring English sources

These features highlight the capacity of CRLs to catalyze protein ubiquitination under distinct cellular contexts and in response to diverse signals.

High density seeding on N-cadherin functionalized and unfunctionalized SLBs places PDCs in distinct cellular contexts and relates to emergent behavior typical for mesenchymal condensation.

The exact mechanisms underlying these discrepancies are unknown, but this might suggest different regulatory processes for kinesin-mediated transport that operate in the distinct cellular contexts of the peripheral sensory neurons and MB neurons.

Therefore, these approaches are reductionists in defining a good biomarker as the most differentially expressed gene or protein when comparing distinct cellular contexts.

To our knowledge this is the first report that demonstrates distinct effects for a single microRNA for the same target gene in distinct cellular contexts.

Collectively, these findings suggest that Lin28A and Lin28B may be involved in tumor progression in distinct cellular contexts and converge on overlapped molecular machineries to inhibit let-7.

However, inactivating ATRX mutations have also been identified in neuroblastoma, pancreatic neuroendocrine tumor, and multiple sarcomas, where they arise in distinct molecular and cellular contexts, indicating that oncogenic mechanisms of broad physiological relevance are likely mobilized by ATRX deficiency6.

The opposing roles of miR-9 in various tissues may be explained by the expression of different mRNA targets in distinct cellular and developmental contexts.

Our study thus reinforces the value of hESCs as tools to model human embryonic development (Murry and Keller, 2008) and emphasizes the importance of analysing the functions of individual members of complex transcription factor networks in distinct cellular and signalling contexts (Spitz and Furlong, 2012).

Strikingly, NANOG and pSTAT3 codependently reactivated Klf4 and K4eRNA in this distinct cellular and environmental context.

It is unclear how podocalyxin mediates these distinct effects in different cellular contexts.