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Several reports have shown that MCLR induces DNA damage in liver cells in vivo [ 10, 25, 26] and in distinct cells types in vitro [ 25, 27– 34], but the mechanism behind the observed DNA breakage is not clear and seems to be dose-dependent and cell-type dependent.
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These cells go on to differentiate into distinct cell types.
The process by which a single fertilized egg undergoes repeated divisions to create the many distinct cell types of an adult animal is known as cell lineage.
Instead, the embryo would grow in the laboratory for about five days to the blastocyst stage, the point at which the embryo has two distinct cell types.
Adult organisms are composed of a number of distinct cell types.
The cochlear nucleus consists of several distinct cell types and is divided into the dorsal and ventral cochlear nucleus.
In general, the simpler the overall organization of the animal, the fewer the number of distinct cell types that they possess.
This is because distinct genes are expressed in distinct cell types.
These are composed of two distinct cell types organised in alternate rows (Figure 2a).
During hematopoiesis, cells originating from the same stem cell reservoir differentiate into distinct cell types.
This way, we achieved selective gene transfer to distinct cell types.
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