Sentence examples for distinct cell types such from inspiring English sources

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Caspase-mediated inhibition of mitochondrial DNA-induced type I IFN production is common among distinct cell types such as hematopoietic stem cells (White et al., 2014) and mouse embryonic fibroblasts (Rongvaux et al., 2014).

An approach more appropriate for this purpose, but also more challenging, would be to reprogram more developmentally distinct cell types, such as fibroblasts, into blood.

Another disadvantage is that previously a reduction of BDNF expression within the CNS could only be achieved in distinct cell types such as astrocytes and as yet poorly defined neuronal subpopulations but not over the entire CNS.

To this end, eQTL profiling of distinct cell types such as monocytes, T cells, and dendritic cells does identify eQTLs that are cell-type specific and not recovered in peripheral blood mixtures (and lymphoblast cell lines appear to be quite different again).

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It is clear, however, that the glycan patterns observed in cancerous cells can be distinct in different cell types, such as core-fucosylation [ 12].

Evolutionist Carl Woese of the University of Illinois, Urbana-Champaign, who proposed the now-accepted classification of the three branches of life (Science, 2 May 1997, p. 699), says it has been unclear how such distinct cell types could have evolved from a single ancestral cell.

A key question is how formation of a β-catenin/ POP-1 complex leads to distinct cellular responses in different tissues and cell types, such as the VPCs and seam cells.

Although this phenomenon is not readily interpretable, the above differential effect of azacitidine suggests the presence of distinct mechanisms of DNA methylation modulation in these cell types, such as targeting cell-type-specific regulatory elements important for CD25 expression.

Since different organs have distinct cell types that express different amounts of structural proteins, a particular structural protein, such as β-actin, cannot be used as an internal standard because its relative abundance in various tissues is different.

Moreover, genetic and cell biological studies based on the differential expression of mutant SOD1 in distinct cell types have demonstrated that although death of MNs causes ALS symptoms, the disease also renders other cells, such as astrocytes and microglia, dysfunctional.

Such similarities include multiple sites and times of blood cell production, the generation of functionally distinct cell types from common hematopoietic precursors, and the utilization of conserved signaling pathways and transcriptional regulators for pro-hemocyte determination and specific lineage differentiation.

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