LCRs are composed of varying numbers of both tissue-specific HSs and non-cell specific HSs, some of which are non-functional, others fulfilling distinct roles in the augmentation of transcription.
Injection of muscarinic antagonists in distinct brain regions cause pronounced augmentation in locomotor activity levels [32], [33], [35] and a hyperactivity phenotype was observed in mouse strains lacking M1 and M4 muscarinic receptors [30], [31], [52] as well as mouse strains null for the nicotinic β2 receptor [29], [36], [37].
Indeed it can be similarly argued that extended sleep deprivation may induce physiological responses that are distinct from, as opposed to an augmentation of, the responses to normal wakefulness.
However, in the case of Rgs7 −/− mice, this augmentation resulted in yet another distinct phenotype: selective deficits in LTD and depotentiation, with normal LTP.
This binding leads to activation of the DCs and an augmentation of a number of phenotypic functions that are distinct from those elicited in DCs activated by TLR ligands or CD40L [2].
These data strongly suggest that the ability of activated Src to induce taxane sensitivity would be mediated by the augmentation of apoptosis through Src to downstream signal transduction pathways distinct from either Ras, PI-3 kinase, or PKC pathway.
Future studies should incorporate factor analysis to establish whether tangibles remain distinct from the other 6 or whether this dimension requires further revision or augmentation.
It has been reported that PLCE1 has an oncogenic role in carcinogenesis of several human cancers, including SCCHN, through distinct mechanisms, such as inflammation, binding to the Ras family small GTPase, and augmentation of angiogenesis [ 13- 16, 26].
Four distinct mechanisms for controlling the solute flux are identified: electromechanical deformation of the membrane, electroosmotic and electrophoretic augmentation of the solute flux within the membrane, and electrostatic partitioning of charged solutes into charged membranes.
Augmentation of creatinine and sustenance of elevated plasma urea concentrations in llamas when fed the LP diet must reflect distinct metabolic adaptations of intermediary protein and/or nitrogen metabolism, not observed in the true ruminants.
Augmentation, not automation.
