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Moreover, hybridization occurs at low rates in the wild and in captivity in Galápagos tortoises when individuals of distinct ancestry meet (e.g., [26]).
Under this interpretation the large anatomical differences between Paleoamericans and Amerindians stem either from in situ stochastic microevolutionary processes [9], or from progressive loss of the diversity originally present in the mother-population at the end of the Pleistocene [10], rather than from distinct ancestry of the two groups.
Bayesian clustering analysis implemented by STRUCTURE [ 23] revealed two (K = 2) genetically distinct ancestry clusters.
Such mapping can, for example, be performed in African Americans and Latinos, revealing a mosaic genome of distinct ancestry.
Consequently, the initial goals of early transethnic studies had been to replicate the associations identified in one population in a second population with a distinct ancestry.
Patients of both Thai and Chinese ethnic origin revealed a higher relative risk from the same allele, despite their distinct ancestry.
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We have, therefore, chosen our study populations from diverse environmental habitats and with distinct ancestries.
We explore the limits of ancestry localization under our approach and find that performance decreases as the number of distinct ancestries and generations since admixture increases.
To confirm that the Rhineland and Khazarian hypotheses indeed portray distinct ancestries, we assessed the degree of background admixture between Caucasus and Semitic populations.
To capture disparate selection pressures and regimes, we have chosen our study populations from diverse environmental habitats and with distinct ancestries.
Compared to the genetic difference between two alleles sampled from distinct ancestries, the genetic difference between two-digit HLA allele classes is more subtle.
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