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We also report that two strains isolated from the infection of a single human host exhibit distinct altered gene expression patterns relative to the unpassaged strain when grown in culture.
For example, common interacting objects were found for distinct altered transcripts and proteins in type 2 diabetes [ 52].
The DNA damage potential and mechanisms for different ENMs seemed to vary and were concentration- and species-dependent, as indicated by the distinct altered molecular expression profiles.
In the CNS, all mutant alleles showed a distinct altered expression pattern as compared to the wild type (further descriptions of the Pros pattern are found in the text and in [Additional file 2]).
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There are three distinct alters, all of them disruptive to the normal order of things, but Tara's teen-age kids, Marshall and Kate Keir Gilchristt and Brie Larson), barely bat an eye at their doings.
The second pathway, demonstrated in this study, is a novel cell contact induced and JAK2-dependent pathway that generates tolerogenic DCs with a distinct altered-mature phenotype that actively suppress T-cell activation.
Interrogating the causes and consequences of altered miRNA expression in CLL cells in common with and distinct from altered miRNA expression in activated B cells will improve our understanding of this disease.
Genome-wide methylation pattern studies on MPN patient samples demonstrate a distinct chromatin altered pattern in PMF when compared to PV/ET patient samples (Nischal et al. 2010).
Second, although distinct significantly altered DNA methylation markers were present in the skin of fetuses with trisomy 18 and trisomy 21, these differences overall were much less dramatic than tissue- and age-related effects.
As for many multifactorial disorders with complex etiologies, a clinical armamentarium for TBI is expected to include a variety of small-molecule pharmaceuticals that target distinct pathways altered by TBI as well as adjunctive treatments, including nutraceuticals, electroceuticals, cognitive behavioral therapies, computer-assisted technologies, and other therapeutic modalities.
Distinct from altering growth cone sensitivity to inhibitory signals, it is important to promote neuronal survival and stimulate axon growth.
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