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Furthermore, H/D exchange analysis defines the dynamic allosteric range of Tyr204 to include the catalytic loop and three additional distant surface regions, which exhibit increased deuterium exchange in the Y204A but not the E230Q mutant.
The upper half is expanded and flattened, looking upward to produce a greatly enhanced superposition image of the dim light filtering down from the distant surface of the ocean.
These easily mutative positions are connected through peptide ligand and define an allosteric mechanism for regulating binding affinity at the α2-β2 groove through molecular interactions at a distant surface site on the α1 helix [39].
Even relatively distant surface electrostatic interactions have been shown to control the redox function of cytochromes.
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The player must solve puzzles using the 'portal gun' or 'Aperture Science Handheld Portal Device', which can create two portals connecting two distant surfaces depicted as matte white, continuous, and flat.
As Byron and Ames watch the moon go dark, the earth casting its shadow on the distant lunar surface, their isolation feels as vast as eternity.
The authors to determine the dynamic responses of reinforced concrete (RC) frame structures when subjected to distant intense surface loadings caused by explosions carried out a numerical study.
It was assumed that the optimal parameters should meet the requirement for delivering cleaning agents to the most distant fiber surface.
Proper control levels of lateral drifts anticipated for reinforced concrete (RC) frame structures within the predefined performance level become crucial when the frame structure is subjected to distant intense surface explosions.
Subcutaneous diverticulae usually exit the thoracic cavity and extend under the skin to distant body surfaces.
route can act as "smart adjuvants" for inducing protective immunity at distant mucosal surfaces while avoiding destructive inflammation.
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