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Such crosses between genetically distant parental lines are an efficient way of maximising genetic variation.
The more distant parental relationship reduced both the number and the size of homozygous regions in patient MD2 compared to patients from MD1.
For example, while B37 × B73 is an intra-heterotic group cross it displayed heterosis levels among traits that were similar to, and sometimes superior to, inter-heterotic group hybrids made between more distant parental genotypes.
The spatial position of the two DH lines between the two distant parental genotypes in the PC2 dimension points to variation in transcript abundance that can be used for genetic studies.
In addition, these data suggest that populations facing rapid environmental change may benefit from introgression and hybridization, even between distant species (the most distant parental strains in our experiment had 14% sequence divergence).
Similar(55)
Researchers should be aware that lagged exposures, even those as distant as parental occupation or childhood neighborhood, may be useful in explaining current health outcomes.
But the accommodations in the far back are so tight they are suitable only for small children seeking distant refuge from parental supervision.
The 4-week observation period was probably too short a time to obtain distant metastases using parental PC-3 cells.
Since retrogenes are often distant from their parental counterparts and lose the original regulatory elements, they are more likely to undergo functional divergence.
When mapped onto a 3D transcript profile space, all PK1-derived subclones clustered around PK1 cells and were more distant from the parental N2a cells and their prion-resistant progeny, R33 and NN2a (Fig 1C and D).
A few years ago, my colleagues and I discovered that the proteasome was able to produce antigenic peptides by assembling peptide fragments that are distant in the parental protein.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com