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Distant imaging of Io was acquired for almost every orbit during the primary mission, revealing large numbers of active volcanoes (both thermal emission from cooling magma on the surface and volcanic plumes), numerous mountains with widely varying morphologies, and several surface changes that had taken place both between the Voyager and Galileo eras and between Galileo orbits.
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The HD study was designed to examine the mass dose effect on pharmacokinetics and to demonstrate the practicability of delivery of F-florbetaben from a production site to distant PET imaging sites, for which product vials containing higher radioactivity are produced to compensate for the radioactive decay during the transportation.
A smaller proportion (9%) of patients had evidence of biochemical recurrence, or locally advanced disease with no signs of distant metastasis on imaging.
Patients were grouped as having regional disease if the fine needle aspiration cytology from draining lymph nodes were found to contain malignant cells, and to have distant metastatic disease if cytology and/or imaging showed presence of distant metastasis.
Therefore, imaging for distant metastases is usually done pre-operatively for anaplastic thyroid cancer and post-operatively for DTCs.
Early tumor recurrence (ETR) was designated as intrahepatic tumor recurrence or distant metastasis detected by imaging tools, pathology and/or high AFP levels within 12 months.
Disease free survival (DFS) was defined from the day of treatment begin to the day of disease local or distant recurrence, diagnosed by imaging examinations according to the RECIST criteria (Response Evaluation Criteria in Solid Tumours) [ 14], death or last follow up.
Distant earthquakes are useful for imaging deep structures, like the mantle plume, and local earthquakes can help to see the shallow chamber.
Staging information gleaned from imaging is helpful in triaging patients to the appropriate method of therapy; in particular, imaging detection of distant metastases prevents unnecessary surgery.
The incidence of metastases is thought to be increasing because of the improved treatment of metastases at other distant sites and advances in imaging techniques, leading to improved detection of central nervous system (CNS) metastases [ 2].
In case of Ca 19-9 increase or clinical evidence for local re-recurrence or distant spread, additional tests or imaging modalities were performed to confirm or exclude disease progression at the discretion of the treating physician.
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