The generated multi-component systems EP and EPHC with fast dissolving capabilities, improved hardness at lower pressures and synergistic effects represent prospective combinations for effective treatment of osteoarthritis and cancer chemotherapy respectively.
A 6 to 9 fold enhancement in % dissolution efficiency was found at 1 min suggesting the fast dissolving capabilities of the eutectic mixtures when compared to plain drug.
NaOCl is widely used in endodontic irrigation because of its antimicrobial activity and tissue-dissolving capability [ 7– 9], which removes the organic component of the smear layer.
These multi-ether functionalized ionic liquids exhibit good capability of dissolving lithium salts.
However, due to carbon dioxide is a non-polar solvent, then, it has low capability for dissolving polar compounds such as polyphenols.
The most commonly used substance in endodontic treatment is sodium hypochlorite (NaOCl), in various concentrations, due to its known antibacterial activity and its capability of dissolving organic tissues [5 7].
ILs generally have high capability to dissolve a wide range of solutes and they are also recyclable.
The above-mentioned system has the capability to dissolve large amounts of drugs with the lipophilic features.
In a study, the terpenes were found to possess the characteristics of n-hexane that substantiate the capability to dissolve the like molecules (Fig. 1).
From all co-surfactants tested (Fig. 3), transcutol HP with HLB value of 4.3 (Rao et al. 2015) demonstrates a good capability to dissolve a large quantity CC and was selected for this research.
