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Dissolution profiles of the tablets were assessed using USP Method II.
USP apparatus I and II are gold standard methodologies for determining the in vitro dissolution profiles of test drugs.
The model successfully predicted the dissolution profiles of the individual tablets (similarity factor, f2 ∼72) manufactured at the targeted set point.
A method for predicting dissolution profiles of directly compressed tablets for a fixed sustained release formulation manufactured in a continuous direct compaction (CDC) system is presented.
The aim of this study was to investigate the use of liquisolid technique in improving the dissolution profiles of naproxen in a solid dosage form.
The stability studies showed that the dissolution profiles of liquisolid tablets prepared with Cremophor® EL were not affected by ageing significantly.
A significant enhancement in the in vitro dissolution profiles of the granules was observed compared to the pure drug and drug excipient physical mixtures.
Dissolution profiles of solid formulations of a poorly soluble model compound were compared in BDM simulating fasted and two levels of fed state.
No significant difference was observed between the dissolution profiles of orifice only on the side of the drug layer and orifices of the same diameter on both sides.
The values for the particle strength of the granules were 1.86 1.97 N/mm2, and the dissolution profiles of the granules were not affected by the tableting process.
The release behavior observed for the three studied drugs was explained considering the measured dissolution profiles of the crystalline drugs, the aerogel composition and its functionalization.
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