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Oxidizing acid mixtures are generally useful dissolution media for many inorganic samples.
Volume of dissolution media changed.
The prepared microspheres were incubated in an enzyme free dissolution media under the same conditions.
The usefulness of selected biorelevant dissolution media (BDM) to predict in vivo drug absorption was studied.
The dissolution media were sodium phosphate buffer, pH 7.0, and ammonium acetate buffer, pH 6.8.
Lack of dissolution information (e.g., missing information on dissolution media volume, individual dissolution data, multimedia dissolution, etc).
The dissolution media could be collected at intervals in the normal way and analyzed to construct a dissolution profile.
In general, the HP-β-CD complex exhibited better dissolution properties than the β-CD complex in various dissolution media.
The results have implications for the design and formulation of both biorelevant and surfactant‐based dissolution media.
These models must also incorporate changes in release due to the dissolution media and methods employed to monitor release.
This study was designed to simulate in vivo conditions regarding temperature, volume, state and composition of dissolution media.
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