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The aqueous solubility was determined by shaking flasks, and the dissolution behavior was evaluated using the paddle method.
Trimethoprim (TMP) was encapsulated into thiolated and pre-activated α-CD derivatives and the dissolution behavior was evaluated in vitro.
Dissolution behavior was measured by conductimetry; the protein structure (native vs denatured) and its initial water activity played an important role, especially influencing powder's wettability.
Dissolution behavior was evaluated in simulated body fluid (SBF) and physiological normal saline solution at 37 °C for up to 28 days.
After soaking for 28 days, noticeable dissolution behavior was observed on the edges of the pores in the BH sample, while the H sample showed no significant difference in morphology.
Although 58% of FEN remained in the crystalline state in the electrosprayed formulation, the dissolution behavior was significantly improved due to decrease in particle size, decrease in crystallinity, and increase in dispersion efficiency.
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The effects of temperature, reaction time and NH4Cl concentration on dissolution behavior were examined.
A brief review of the experimentally observed dissolution behavior is presented, thus motivating the modeling of the mechanism of dissolution.
The investigation of mineral dissolution behavior is important when this BLCA use as a carrier for therapeutic agents in orthopaedic and dental implant applications.
For other silicates and aluminum bearing minerals, dissolution behavior is more complex [2 20].
Complex dissolution behavior is observed in certain minerals in carbonate rocks such as dolomite (CaMg (CO3 2), calcite (CaCO3) and magnesite (MgCO3) (Hiorth et al. 2010).
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