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EBs were formed by mechanical dissociation of cell clusters and plating into low-adherence dishes in hESC medium without bFGF2 for 7 days.
Dissociation of cell:cell contact here appears to be acting to initiate differentiation and promote the acquisition of a transitory cell state in which the cells are primed to differentiate but not yet specified to either cell lineage.
Differential cell elongation occurring during root bending would theoretically induce longitudinal strains on the tissue, facilitating dissociation of cell walls in the same zone where the primordium appears and will potentially emerge.
Relevant to this paper, this agent has been reported to cause dissociation of cell contact, leading to changes in morphology and behavior that spurs individual motility [ 36].
Treatment of EBV-transformed B cells with ⩾2 μ M of simvastatin, atorvastatin, or lovastatin resulted in dissociation of cell clumps and death beginning 5 days after treatment with the drug (Katano et al, 2004).
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Reduced cell-cell adhesion coincided with the partial dissociation of cells from the ECM.
Thus, the cells remain in a confluent layer with no piling up or dissociation of cells from the monolayer.
The development of metastases involves the dissociation of cells from the primary tumor to penetrate the basement membrane, invade and then exit the vasculature to seed, and colonize distant tissues.
There were no significant differences in inflammatory cell accumulation or the number of apoptotic epithelial cells between SOPtenΔ/Δ lungs and control lungs, but the SOPtenΔ/Δ lungs demonstrated a loss of TJ morphology and a dissociation of cell-cell contacts after the injury.
The dissociation of cells was completed mechanically using a glass micropipette by pipetting up and down.
Dissociation of cells from an extracellular matrix leads to the rapid induction of cell death processes, most frequently termed anoikis (Greek for homelessness).
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CEO of Professional Science Editing for Scientists @ prosciediting.com