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Most infections are asymptomatic but in some individuals, especially if immunocompromised, the parasite can become widely disseminated causing severe clinical signs including encephalitis [ 5].
Toxoplasmosis is one of the opportunistic infections which in people with immunocompetent is largely asymptomatic, but in immunocompromised individuals, the parasite can become widely disseminated, causing severe toxoplasmosis [ 2– 4].
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This might help C. albicans overcome the mechanical and biological defenses of the tissue and allow it to disseminate, causing severe infections.
A large proportion can also disseminate, causing viremia and potentially invading the central nervous system [ 41].
In the absence of parasites and predators that had kept their numbers in check in their European habitat, they multiplied and disseminated rapidly, causing widespread destruction of the native vegetation.
Amastigotes replicate intracellularly and spread to new macrophages, disseminating and causing disease [1], [2].
Mycobacterial disease is a frequent cause of illness in AIDS patients with the majority of these patients having disseminated disease caused by Mycobacterium avium Complex (MAC).
Mycobacterial disease is a frequent cause of illness in AIDS patients with the majority of these patients having disseminated disease caused by MAC.
Disseminated disease caused by nontuberculous mycobacteria (NTM) has been described for HIV-infected patients with CD4 counts <50 cells/mm.
From the 1970s onward, W ST-11 strains disseminated to cause sporadic disease and case clusters globally (Cluster 2).
During the last five decades, S. aureus clones that resist methicillin (methicillin-resistant S. aureus, MRSA) disseminated and caused medical and public health problem worldwide [ 17, 18].
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