During colonization, epithelial cells first activate the EMT programme to disseminate from a primary tumour to reach a distant tissue site.
However, the molecular mechanism by which cancer cells acquire the ability to disseminate from primary tumors, seed distant organs, and grow into tissue-destructive metastases remains incompletely understood.
A small subset of patients will suffer long-term health problems; in fewer still, cocci will disseminate from the lungs into other tissue — skin, bones, and, often fatally, the meninges of the brain.
A small subset of patients will suffer long-term health problems; in fewer still, cocci will disseminate from the lungs into other tissue skin, bones, and, often fatally, the meninges of the brain.
Heparin binding haemagglutinin adhesin (HBHA) enables M. tuberculosis to bind to sulphated glycoconjugates on epithelial cells; disruption of its synthesis severely impairs the ability of bacteria to disseminate from the lungs to the spleen.
After the first press releases about the object, when his phone began ringing constantly with calls from reporters and meteorite collectors and interested institutions and friends, he chose a careful approach, allowing just one camera crew to film inside his house, and letting the stories disseminate from that coverage only.
Interestingly, in patients with glioma, tumour cells can disseminate from the brain to other tissues via the bloodstream, but very rarely give rise to overt extracranial metastases, except when organs from such patients are transplanted into immunosuppressed recipients18,19,20,21.
In some cases, cancerous cells can disseminate from the original tumor and invade various organs and tissues, a process known as metastasis.
Targeted therapeutics are designed to focus on actionable mutations detected in a biopsy of the primary tumor, but these "actionable" mutations may no longer drive disease progression once tumor cells disseminate from the primary carcinoma and undergo unique genomic changes.
The designs on the wall currently everything from security guard uniforms to shopping bags to billboards eventually disseminate from this cramped cluster and define the museum to a greater audience.
4TO7 cells can disseminate from primary mammary tumors into the lungs but don't form visible lung nodules.
