Sentence examples for disruptive effect on cell from inspiring English sources
Although we have shown that abrogating pRb function in osteoblasts has a disruptive effect on cell adhesion, it remains to be established whether altering the function of upstream components of the pRb pathway such as CDK4, cyclin D, and p16ink4a, will have similar consequences for intercellular adhesion.
Polymyxin B sulfate shows a locally disruptive effect on cell wall integrity of gram-negative bacteria and induces pore formation in the membrane.
Furthermore, high-intensity US possibly also has a disruptive effect on the bacterial cell wall itself, leading to cell death.
Similar to homotypic spheroidization, B49Mod1 does not have significant spheroidization disruptive effect on shBST-2 cells (Fig. 5D).
They have also demonstrated that CPF exposure at doses below the threshold for systemic toxicity and inhibition of brain cholinesterase exerts disruptive effects on neural cell development, with respect to DNA synthesis, gene transcription, cell differentiation, and synaptogenesis [ 31].
It is possible that synchrony among cells would occur in-vivo if not for the disruptive effects of cell division.
Unlike the effect of B49Mod1 on BST-2-expressing shCTL cells (Fig. 4B), the peptide does not have further spheroid disruptive effect on BST-2-suppressed shBST-2 cells (Fig. 4D).
This disruptive effect on stress fibers significantly increased doxorubicin-induced cell detachment in WT and ROCK1−/− cells.
Although some miRNAs have been shown to exert a disruptive effect on skeletal muscle differentiation at least in cell culture models [ 70], in most cases, it remains to be established whether the changes in miRNA expression levels are causally involved in these diseases or are secondary to the degeneration/regeneration response of the affected muscle tissue.
LTX-302 displayed a selective disruptive effect on the tumor plasma membrane, leading to necrosis of the tumor cells.
They produced a disruptive effect on the bacteria wall while their internalization was hindered on the eukaryotic cells.
