Fear of that magnitude is disruptive and a burden, and we may yet decide to push it aside..
Fear of that magnitude is disruptive and a burden, and we may yet decide to push it aside.
Disruptive change can burden the morale of the group.
Europeans cannot conceal their embarrassment over their Common Agricultural Policy that is creating an almost unbearable economic burden, inspiring disruptive trade practices and building mountains and lakes of surplus commodities to prop up the incomes of their farmers.
Purcell, S.M. et al. A polygenic burden of rare disruptive mutations in schizophrenia.
Purcell, S. M. et al. A polygenic burden of rare disruptive mutations in schizophrenia.
Despite the striking degree of genetic heterogeneity, case-control studies have detected specific burden of rare disruptive CNV for neuronal and neurodevelopmental pathways.
Although these variants were rare, we still investigated their functional consequences based on recent evidence proposing a polygenic burden of rare disruptive mutations in schizophrenia and neurodevelopmental disorders (41).
Caregivers may experience financial burdens, difficulty handling disruptive behavior and fluctuating emotions that cannot be controlled, a lack of time for personal enjoyment and social engagement, difficulty handling the lack of motivation found in the mentally ill family member, and financial difficulties [ 1, 2].
Patient stressors such as negative and disruptive symptoms have been linked to increased burden in caregivers of patients with schizophrenia.
In addition, all of these disorders either have a high global burden rating or are highly disruptive to a person´s life.
