Severe oxidative stress resulted in a significant (p<0.001 vs untreated controls) loss of TER (Figure 4A) caused by disruption in the pattern and loss of tight junction protein expression (Figure 4B,C,D) and significant cell death (p<0.001 vs controls) (Figure 4E).
It has been suggested that disruption in the pattern separation function of the dentate gyrus may underlie some of the clinical features of schizophrenia (Tamminga et al., 2010).
Aβ measurements in human cerebrospinal fluid revealed age-related disruptions in the normal circadian pattern and a negative correlation with the amount of sleep received [ 11].
The program loses control, creating design disruptions in the final patterns (and logos).
Disruptions in the neurogenesis-dependent pattern separation function of the dentate gyrus have been suggested to underlie some of the clinical features of schizophrenia (Tamminga et al., 2010).
The title "Sunken Area" could be a reference to three specific elements in the photograph: the disruption in the shadowed pattern of the vinyl-sided wall where a dent occurs, the concave form of the concrete sidewalk or driveway that abuts the wall and the space between the two that accommodates some pesky weeds.
The therapist becomes alert to movement in language, to the disruption in the speech pattern, to the elements of surprise or reflection that halt a well-honed tale in its tracks, so that story or incident can be thought and felt about anew.
At this early stage there were no signs of disruption in the alternating pattern of podial organization, which in other echinoids is a by-product of the alternating deposition of plates known as the "ocular plate rule" [30].
This phenotype was first appreciable at 4 dpf and was manifested as a disruption in the uniform pattern of melanophores arranged along the lateral stripes (Fig. 8B,D, brackets).
Disruptions in the central-periphery patterns of distribution were also recorded in several waterbird species associated with woodland habitats; although, this kind of environment is expected to provide only moderate variation in the physical quality of nesting sites, most commonly expressed by variation in tree height and canopy structure.
