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The membrane localization of ZnPc molecules led to rapid membrane disruption upon irradiation and subsequent necrosis-like cell death.
In the ordered state, the nanocomposite possesses a higher modulus, but an apparently weaker FS network (due possibly to network disruption upon copolymer ordering).
Each healing process starts with haematoma formation (Fig. 2) in the inflammatory phase, simply resulting from blood vessel disruption upon injury and fracturing of the bone (Opal 2000).
In contrast, both OGlcNAcylation and phosphorylation disrupted the α-helix at the C-terminus of α-helices, with greater α-helical disruption upon phosphorylation than OGlcNAcylation.
To minimize IFP structural disruption upon fusion of fragments to termini having this separation, 12 residue glycine-rich linkers were used for library construction.
Thus we wanted to determine whether Golgi disruption upon CLASP1 knockdown affects cell shape and cell adhesion, modulation of which are crucial for cell migration as a precursory step for neurite extension in N1E-115 cells.
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Furthermore, retrotransposable elements tend to select tRNA genes as chromosomal integration sites [ 44], appearently in order to avoid gene disruptions upon retrotransposition.
There will come a time when nature metes out such sustained and brutal punishment that even the most cynical deniers will have to acknowledge climate disruption is upon us.
Consistently, the Mdm4 protein half-life was significantly shortened upon Rps27l disruption in MEFs or upon RPS27L knockdown in H1299 cells, but significantly extended upon ectopic expression of RPS27L in H1299 cells.
A previous study demonstrated that Vangl2 is a phosphorylation target upon Wnt5a/Ror2 signaling, and Vangl2 polarization is lost upon disruption of Wnt5a signaling in chondrocytes (Gao et al., 2011).
The first-day disruptions forced upon him the requirement to play 25 holes, a factor arguably in the loss of concentration on his back nine.
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