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Beyond a global rise in austerity and digital disruption, the key challenge facing luxury brands is how to keep up with the unprecedented pace of the ever-evolving new luxury consumer.
As mentioned above, TALENs are effective tools for gene disruption; the key point for the application of TALENs is fast and efficient assembly.
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Announcing a service closure for example will create disruption, but the key is to be responsive and flexible in helping people invent and create high quality alternatives.
The BBB breakdown following tight junction disruption is the key mechanism of IAE pathogenesis16; however, the detailed mechanism for this process is still not understood.
6 64 65 Recently, it has been proposed that this higher endotoxaemia in ob/ob mice and db/db mice was dependent on a disruption of the key tight-junction proteins, ZO-1 and occludin.
However, spatial memory impairments are present following both increases and decreases in hippocampal ACh (Bunce et al., 2004; Elvander et al., 2004), suggesting that ACh disruption may be the key factor, rather than ACh depletion per se.
This paper lays out a conceptual model of first and second order disruptions and identifies the key factors necessary for modelling the process that results in second order disruptions a process that necessarily occurs at the intersection of several highly-complex interactive systems.
Genetic modifications that have led to increased hydrogen yields in E. coli have thus far focused on the disruption of key metabolic genes of the mixed acid fermentation pathways of E. coli, and of specific regulators of the FHL system.
The detrimental effects of antimicrobials include the disruption of key microbial processes in soil, toxicity to organisms, and the development of microbial resistance [107] [110].
The treatment of low probability events leading to core disruption is one of the key issues of R&D plans for the advanced reactor systems in general, and for sodium fast reactors in particular.
The key disruption here is the customer on-boarding model: you can register as a client with your Facebook account, or you can get legitimated by sending in some documents or affiliations (such as another bank account), or go through a full "know your customer" process.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com