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Because lysis of bacterial cells generally requires both an endolysin and a holin - membrane disruption (the function of the holin) is considered to be requisite for the endolysin to attack the peptidoglycan [ 19] - understanding the phylogenetics and genomic context of these genes are important milestones to develop biotechnological applications.
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In addition, it has been suggested that disruption of the function of kinetochore by the extensive DNA damage is able to delay mitotic exit by disruption of kinetochore functions but not by ATM-dependent mechanisms (Mikhailov et al, 2002).
Disruption of the function of the genes in the GA or SL biosynthetic or signaling transduction pathway could result in various phenotypes such as dwarf6 and excessive outgrowth of axillary buds,88,89 respectively.
Angelman syndrome is caused by a disruption in the function of the UBE3A gene on the maternal chromosome 15.
Overall, this implies that the disruption of the function of the paraspeckles is correlated with the increasing signs of deterioration of normal transcriptomic state of the cells.
Simultaneous disruption of the function of all three RACK1 genes results in lethality.
These findings suggest that disruption of the function of Beclin-1 and other autophagy genes may contribute to the pathogenesis of human cancers.
It has been suggested that the superior clinical efficacy of tubulin inhibitors is due to disruption of the function of microtubules in interphase cells [ 38].
Does this assumption appear reasonable?" Obviously, no one would propose that a candy bar or a meal of Chinese food would constitute disruption of the function of the endocrine system; but they do change hormone concentrations in the blood.
Disruption of the function of the genes in the GA or SL biosynthetic or signaling transduction pathway could result in various phenotypes such as dwarf and excessive outgrowth of axillary buds, respectively.
Offline disruption of the function of this area shortened dominance durations (increased switch rates) in binocular rivalry compared to no stimulation, whereas stimulating a control site (the homologous locus in the left hemisphere) did not.
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