Sentence examples for disruption the function from inspiring English sources

Because lysis of bacterial cells generally requires both an endolysin and a holin - membrane disruption (the function of the holin) is considered to be requisite for the endolysin to attack the peptidoglycan [ 19] - understanding the phylogenetics and genomic context of these genes are important milestones to develop biotechnological applications.

In addition, it has been suggested that disruption of the function of kinetochore by the extensive DNA damage is able to delay mitotic exit by disruption of kinetochore functions but not by ATM-dependent mechanisms (Mikhailov et al, 2002).

Overall, this implies that the disruption of the function of the paraspeckles is correlated with the increasing signs of deterioration of normal transcriptomic state of the cells.

Simultaneous disruption of the function of all three RACK1 genes results in lethality.

These findings suggest that disruption of the function of Beclin-1 and other autophagy genes may contribute to the pathogenesis of human cancers.

It has been suggested that the superior clinical efficacy of tubulin inhibitors is due to disruption of the function of microtubules in interphase cells [ 38].

Does this assumption appear reasonable?" Obviously, no one would propose that a candy bar or a meal of Chinese food would constitute disruption of the function of the endocrine system; but they do change hormone concentrations in the blood.

Probe AFA showed a 4-fold decrease in Kd values, which indicated that insertion of FAP had no obvious disruption on the function of the double affibody, and recapitulated the avidity-based binding enhancement previously reported.

Offline disruption of the function of this area shortened dominance durations (increased switch rates) in binocular rivalry compared to no stimulation, whereas stimulating a control site (the homologous locus in the left hemisphere) did not.

Disruption of the function of the genes in the GA or SL biosynthetic or signaling transduction pathway could result in various phenotypes such as dwarf and excessive outgrowth of axillary buds, respectively.

Increase in water problems in the basin of Lake Balkhash, associated with extensive development of the water sectors for the economy, leads to disruption of the functioning sustainable, natural and economic systems of the region.