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The occurrence of these sickness behaviors among individuals suffering circadian disruption strongly suggests that a disrupted circadian organization adversely affects a patient's quality of life.
Carotenoids represent an example of micronutrients for which processing-induced food structure changes (e.g., matrix disruption) strongly influence their bioavailability.
The high frequencies of gene disruption strongly support the likelihood of achieving a desired genotype, in which each copy of the target gene is functionally knocked out in 1% to 50% of all cells [ 17, 18].
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This pattern -- obscure species' bursting to the fore, as the trumpet did, in the wake of an ecological disruption -- "strongly reminds one of the situation between mammals and dinosaurs," Dr. Eldredge wrote in a recent paper.
The results of the first experiment (N= 24) showed that the annoyance assessments were indeed altered by the experience of disruption, most strongly during, and to a lesser extent after task completion, whereas ratings of the non-disruptive sounds remained largely unaffected.
In our previous study, EPIS disruption was strongly associated with CSF in uveitic ME but appears to be independent of the site of inflammation [ 2].
The increased PM localization of Cat1-GFP caused by the arn1 disruption was strongly correlated with the high canavanine sensitivity in arn1Δ and tsc2Δ arn1Δ (Fig. 2A).
Finally, a quantification study showed significant increase in the disrupted NB and IC populations after the drug treatments, and the disruption indices were strongly correlated in each testis.
Melittin disruption mechanisms depend strongly on the geometry of the lipid layer; however, despite the interplay between layer geometry/thickness and melittin activity, results indicate that the presence of lipid heterogeneity and lateral phase separation greatly influences the disrupting efficiency of melittin.
(Genova, 2014) In 2013, Maranzana and his colleagues reported that in both purified bovine mitochondria and reconstituted liposomal preparations, the disruption of SC strongly enhance the generation of superoxide and H2O2 by CI. (Maranzana et al., 2013) The structural explanation of SC preventing ROS formation is still lacking.
M. tuberculosis has an mgtC gene, the disruption of which strongly attenuates virulence in both macrophages and mice [43].
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