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Offense is based on timing, and defense is generally based on the disruption of timing.
"Offence is based on timing, and defence is generally based on the disruption of timing".
Thus,despite maintenance of robust core circadian clock function in non-resonant mice, disruption of timing was evident in a number of key clock-output pathways.
Some of the most interesting work on this subject has utilized animal models to assess the physiological effects that disruption of timing has on disease progression.
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Master the art of timing.
Sharpen your sense of timing.
Disruption of clock timing has also been shown to contribute to an array of nervous system disorders.
Given that there are multiple circadian clocks in the body, how does disruption of their timing by light affect disease?
In either case, a delay in closing of the neural tube is associated with deficits in midline brain development due to disruption of the timing of critical events of early brain development.
This suggests that a synchronized circadian system may be broadly important for normal cognition and that the consolidation of memories may be particularly sensitive to disruptions of circadian timing.
The misaligned feeding treatment did not result in an overall decrease in amount of sleep, but instead had a severe impact on the temporal pattern, suggesting that this treatment acts via disruption of the circadian timing of sleep.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com