Sentence examples for disruption of the type from inspiring English sources

Curiously, yeast mtRNase P function is impaired by disruption of the type II fatty acid synthesis (FAS II) pathway [73].

As in the Fas DD/FADD DD complex, disruption of the type IIa interface by the N150K mutation did not show a distinct effect on complex formation.

This finding is consistent with the previous observation that disruption of the type IIb interface on Fas DD did not block formation of the Fas DD/FADD DD complex.

Consistently, homozygous disruption of the type II receptor of the TGF-β gene (Tgfbr2) in Apc1638N mice causes malignant transformation of the intestinal adenomas induced by Apc mutation [38].

The balance between cell proliferation and cell death is important to maintain equilibrium in different tissues, and a disturbance in this balance may lead to tumour development [ 34] since the disruption of this type of regulation is a characteristic of tumours.

Disruption of the wild-type lactate dehydrogenase gene in A. oryzae LDH improved lactate production.

It has been reported that disruption of the α-type subunit of the SnRK1 complex retards seed germination in rice [35].

MD simulations show that the disruption of the wild-type CA C-terminal domain can destabilize the CA−CA dimerization and thus inhibit HIV viral assembly.

Antimorphic or DN mutations, as subsequently described by Herskowitz, have been defined as disruption of the wild-type activity by the mutant polypeptide (Table 1).

Disruption of the P-type ATPase resulted in a non-vectored phenotype [ 23], whereas disruption of the solute binding protein of a putative glucose ABC-transporter led to a reduced level of transmission [ 27].

Although transformation of X-33 and GS115 strains with linearized constructs favor single crossover recombination at the AOX1 locus and generates a Mut+ phenotype, double crossover recombination that results in the disruption of the wild-type AOX1 gene and the generation of a MutS phenotype is possible.