Sentence examples for disruption of the second from inspiring English sources

However, disruption of the second Egr-1 binding site in position -62 pRad-155m22) resulted in a weaker induction of the Rad promoter activity by Egr-1* (∼7 folds) compared with the 25-fold activation in the pRad-155 construct, whereas the basal level remained unchanged.

We generated Dicer1-deficient mice from an ES cell (RFF266), which was obtained from Bay Genomics [34], carrying a gene trap insertion between exon 22 and exon 23, resulting in disruption of the second RNaseIII domain and loss of the double-stranded RNA-binding domain.

In previous studies, three out of 13 samples with loss of one 5q allele exhibited a disruption of the second GRAF allele by insertions (Borkhardt et al, 2000).

It is very likely that disruption of the first cell death checkpoint generates a qualitatively and quantitatively different response to TNF-induced cell death when compared to disruption of the second cell death checkpoint.

Disruption of the second carbamoyltransferase, plu4565, did not affect phurealipid biosynthesis, although these mutants were no longer able to produce a virulence factor that we termed " Photorhabdus clumping factor" or "PCF",[ 8] the structure of which is currently unknown.

The choice of including this part of the gene was consistent with the idea to simulate by VIGS what seems to be the case in tomato, where the disruption of the second exon by a stop codon causes the abolishment of the DUF623 domain and thus the change in fruit shape [ 2].

The discovery caused a brief disruption on the second floor of the Senate side of the building as the Capitol police quarantined the area around Mr. Daschle's office suite.

In this study we demonstrated successful disruption of the first step of phytic acid biosynthetic pathway in transgenic rice plants, by silencing the gene expression of the enzyme myo-inositol-3-phosphate synthase.

The Lark Ascending (27 July): This elegiac piece for solo violin and orchestra was composed in 1914 but received its premiere in 1921 owing to the disruption of the First World War.

A diminution in the myo-inositol content of transgenic plants was also observed due to disruption of the first step of phytic acid biosynthetic pathway, which further reduced the level of ascorbate and altered abscisic acid (ABA) sensitivity of the transgenic plants.

Disruption of the first Egr-1 binding site in position -74 pRad-155m11) causlightslight decrease in the Rad promoter activity but the induction upon Egr-1* overexpression remain unchanged (Figure 2B).