Sentence examples for disruption of the basic from inspiring English sources

She identifies the deepest insults inflicted by involuntary unemployment — the disruption of the basic routines of eating and sleeping, the awful aloneness, the doubts, the drift.

While this does not in and of itself translate to a cure, the discovery provides direction for researchers to investigate possible points of disruption of the basic pathway of FOP.

Remodelling of chromatin can be achieved in several different, but interconnected, ways: (1) covalent modification of histones, (2) exchange of 'generic' core histones with histone variants, (3) disruption of the basic nucleosome structure and histone DNA contacts, and (4) modification of the DNA itself.

In vivo ChIP analysis supports this notion, as despite the presence of the MBD and two functional AT-hooks in both MeCP2-G273X MeCP2-R306C306C, the disruption of the basic cluster in MeCP2-R306C reduces binding to DNA even more than the complete absence of the cluster in MeCP2-G273X.

While full length PSIP1 contains additional DNA binding domains [ 16, 35], disruption of the PWWP basic surface markedly reduces in vivo chromatin binding ability of full-length PSIP1 as shown in this work and previously [ 27].

However, as discussed above, this present study does not provide any explicit support for the assumption of endocrine disruption as the basic mechanism of action.

Even if there has not been a disruption of the big banks, basic financial services available to consumers are changing rapidly, nonetheless.

Surprisingly, mutating the TRD is more detrimental than deleting the entire C-terminus, indicating a dominant-negative effect on MeCP2 function, likely due to the disruption of a basic cluster.

By Monica Awad GAZA, Occupied Palestinian Territory, 25 July 2008 –  Every day, children and adolescents throughout the Gaza Strip suffer from the disruption of basic services and deteriorating living standards.

Organized 'recreation days' relieve stress for children in Gaza GAZA, Occupied Palestinian Territory, 25 July 2008 – Every day, children and adolescents throughout the Gaza Strip suffer from the disruption of basic services and deteriorating living standards.

Villagers expressed anger not only at the casualties and destruction, but also at the disruption of basic human needs, saying they had been led to believe humanitarian aid would quickly follow the military strike.