Sentence examples for disruption of such from inspiring English sources

Given this proposed contribution of TNR hairpins to the expansion mechanism, disruption of such structures via strand invasion offers a potential means to negate the disease-initiating expansion.

The disruption of such peptide peptide cation-π interactions is certainly relevant for peptide design in β-sheets or β-hairpin structures, but it could also have implications for astrobiology.

Disruption of such pathological interactions in the field of a developing primary or secondary tumour is, therefore, required to disable the malignant population and arrest progression without tissue destruction.

The disruption of such interactions remains a challenging feat but, in recent years, there has been considerable progress in the design of proteomimetics: molecules that mimic the structure and function of extended regions of protein surfaces.

An extension of such a hypothesis is that certain sleep pathologies may be related to disruption of such coordinated behavior.

In this framework, our theoretical results show that pathogenic mutations facilitate the disruption of such interactions, acting as effectors for the detachment process.

The cytosol of a cell maintains cellular homeostasis including redox potential, ionic levels, etc. Disruptions of such homeostasis (biomarkers of aging) will initiate damage to cells.

Changes considered disruptions of such mechanisms from exposure to environmental agents must be a function of the levels and timing (i.e. relative to plausible critical or vulnerable periods) of the exposure; the SOA Assessment's analyses are hampered by not evaluating these nuances.

The disruption of hemoproteins, such as cytochromes b 5 and nitric oxide synthase, possibly increases ROS production.

For example, in Drosophila, the disruption of genes such as Oskar, Vasa, Tudor, Germ cell-less and Aubergine results in the lack of a germ line (35).

The floods, the severest in Guyana in over a century, have resulted in loss of livelihoods, disruption of services such as health and education, the threat of disease and the weakening of infrastructure.