The implicated region overlaps most of 16p11.2, a cytogenetic region in which duplications are well known to cause disruption of speech and language development (35), and this event was considered very likely pathogenic.
A pack of attacking startups sounds something like a pack of ravenous hyenas, but, generally, the rhetoric of disruption — a language of panic, fear, asymmetry, and disorder — calls on the rhetoric of another kind of conflict, in which an upstart refuses to play by the established rules of engagement, and blows things up.
Standing at the bleeding edge, gazing into the red-rimmed, bottomless abyss of disruption, the normal rules of language break down and a Dadaist imperative asserts fresh claims of absurdist relevance.
This disruption of otherwise plain language breeds uncertainty.
This would suggest that the phenotype observed in the KE family stems from disruption in the underlying neural circuits of language development, an idea that has received support from animal studies (see below).
Current neuropsychological models of these symptoms stress the importance of disruptions in language processing and mnemonic functions [ 1, 23].
"Hush" addresses the limits and assets of language and communication and the disruption to society when communication breaks down.
Disruption of the FOXP2 gene causes a severe form of language impairment in some rare cases (Lai et al. 2001).
This may reflect the simultaneous disruption of signaling in dorsal and ventral language processing streams.
According to this concept, Crow [14], [15] concluded that the core deficit is disruption of the left-hemispheric shift for language, especially those components relating to phonological articulation, a distinct linguistic process located in left dorso-lateral pre-frontal cortex.
