Sentence examples for disruption of contact from inspiring English sources

Using normoxic saponin-permeabilized heart muscle fibres, we showed that dissociation of HK2 from mitochondria by treatment with G-6-P at pH 6.3 led to decreased rates of extramitochondrial PCr synthesis consistent with disruption of contact sites (Pasdois et al., 2012).

If the disruption of contact-mediated signaling influences the efficiency of acinar-to-islet cell conversion, loss of physical contacts between cells could replace molecular manipulation.

Disruption of contacts at the C-terminus of helix 5 was shown previously to decrease the activity of procaspase-3 [ 34].

Furthermore, disruptions of contact inhibition via AhR-dependent induction of JUN-D/cyclin [ 168] have been observed.

Disruption of cell ECM contact triggers contact-free cell death, termed anoikis.

CSF-1R activation in MCF-10A cells induces cell-cell adhesion disruption, loss of contact inhibition, growth in soft agar, and enhanced cell motility [8], [41].

Peritoneal dissemination of ovarian carcinoma is mediated by epithelial mesenchymal interconversions leading to the disruption of cell cell contact and modulation of cell extracellular matrix (ECM) interactions.

The sole exception (R223A) can be attributed to weaker binding of the ternary complex to the ribosome, resulting from disruption of a contact that forms between them.

(17) It is unclear, however, whether this loss of activity arises from disruption of protein contact(s) to the bulged-G nucleobase or from indirect effects.

The earlier observed disruption of cell cell contact between β cells (and therefore function, see Fig.  4E) by α-cell mislocalization could potentially explain such an outcome.

The disruption of physical contact between monocytes and CD4+ or CD8+ TIS-T cells completely abrogated the ability of TIS-T cells to potentiate Mo/Ma production of TNF, IL-1 β, IL-6 and IL-8.